<?xml version='1.0' encoding='UTF-8'?><?xml-stylesheet href="http://www.blogger.com/styles/atom.css" type="text/css"?><feed xmlns='http://www.w3.org/2005/Atom' xmlns:openSearch='http://a9.com/-/spec/opensearchrss/1.0/' xmlns:georss='http://www.georss.org/georss' xmlns:gd='http://schemas.google.com/g/2005' xmlns:thr='http://purl.org/syndication/thread/1.0'><id>tag:blogger.com,1999:blog-5823906349768938190</id><updated>2011-11-27T16:46:11.805-08:00</updated><category term='neurostar'/><category term='mental illness'/><category term='depression'/><category term='ttranscranial magnetic stimulation'/><category term='rTMS'/><title type='text'>Chandler TMS</title><subtitle type='html'>Transcranial Magnetic Stimulation</subtitle><link rel='http://schemas.google.com/g/2005#feed' type='application/atom+xml' href='http://chandlertms.blogspot.com/feeds/posts/default'/><link rel='self' type='application/atom+xml' href='http://www.blogger.com/feeds/5823906349768938190/posts/default?max-results=100'/><link rel='alternate' type='text/html' href='http://chandlertms.blogspot.com/'/><link rel='hub' href='http://pubsubhubbub.appspot.com/'/><author><name>Chandler TMS</name><uri>http://www.blogger.com/profile/17516475112889955131</uri><email>noreply@blogger.com</email><gd:image rel='http://schemas.google.com/g/2005#thumbnail' width='16' height='16' src='http://img2.blogblog.com/img/b16-rounded.gif'/></author><generator version='7.00' uri='http://www.blogger.com'>Blogger</generator><openSearch:totalResults>2</openSearch:totalResults><openSearch:startIndex>1</openSearch:startIndex><openSearch:itemsPerPage>100</openSearch:itemsPerPage><entry><id>tag:blogger.com,1999:blog-5823906349768938190.post-1468638523833546462</id><published>2010-04-03T10:21:00.000-07:00</published><updated>2010-04-03T10:21:33.724-07:00</updated><category scheme='http://www.blogger.com/atom/ns#' term='ttranscranial magnetic stimulation'/><category scheme='http://www.blogger.com/atom/ns#' term='mental illness'/><category scheme='http://www.blogger.com/atom/ns#' term='depression'/><category scheme='http://www.blogger.com/atom/ns#' term='neurostar'/><category scheme='http://www.blogger.com/atom/ns#' term='rTMS'/><title type='text'>Is TMS needed ?????</title><content type='html'>&lt;div style="direction: ltr; language: en-US; margin-bottom: 0pt; margin-top: 4.2pt; mso-line-break-override: none; punctuation-wrap: hanging; text-align: left; unicode-bidi: embed; vertical-align: baseline;"&gt;&lt;span style="color: black; font-family: Arial; font-size: 10.0pt; language: da; mso-ascii-font-family: Arial; mso-bidi-font-family: +mn-cs; mso-color-index: 1; mso-fareast-font-family: +mn-ea; mso-font-kerning: 12.0pt;"&gt;The National Comorbidity Survey, which is the most up to date estimates of the prevalence and consequences of major psychiatric disorders in the US population,&amp;nbsp;has estimated that in any one year period of time, there are an estimated 14 million US adults who meet formal diagnostic criteria for Major Depressive Disorder.&lt;span style="mso-spacerun: yes;"&gt;&amp;nbsp; &lt;/span&gt;Of these 14 million adults&lt;b&gt;, only half (about 7.2 million individuals) seek treatment within the health care system.&amp;nbsp;&lt;span class="Apple-style-span" style="font-weight: normal;"&gt;Of these 7.2 million treated patients, the&amp;nbsp;National Comorbidity Survey&amp;nbsp;estimated that about &lt;b&gt;4 million people remain poorly served by existing treatments.&lt;/b&gt;&lt;/span&gt;&lt;/b&gt;&lt;/span&gt;&lt;/div&gt;&lt;div style="direction: ltr; language: en-US; margin-bottom: 0pt; margin-top: 4.2pt; mso-line-break-override: none; punctuation-wrap: hanging; text-align: left; unicode-bidi: embed; vertical-align: baseline;"&gt;&lt;span style="color: black; font-family: Arial; font-size: 10.0pt; language: da; mso-ascii-font-family: Arial; mso-bidi-font-family: +mn-cs; mso-color-index: 1; mso-fareast-font-family: +mn-ea; mso-font-kerning: 12.0pt;"&gt;&lt;b&gt;&lt;span class="Apple-style-span" style="font-weight: normal;"&gt;&lt;b&gt;&lt;/b&gt;&lt;/span&gt;&lt;/b&gt;&lt;/span&gt;&lt;/div&gt;&lt;b&gt;&lt;b&gt;&lt;div style="direction: ltr; language: en-US; margin-bottom: 0pt; margin-top: 3.24pt; mso-line-break-override: restrictions; punctuation-wrap: simple; text-align: left; unicode-bidi: embed; vertical-align: baseline;"&gt;&lt;span style="color: black; font-family: Arial; font-size: 9.0pt; language: en-US; mso-ascii-font-family: Arial; mso-bidi-font-family: +mn-cs; mso-color-index: 1; mso-fareast-font-family: +mn-ea; mso-font-kerning: 12.0pt;"&gt;&lt;span class="Apple-style-span" style="font-weight: normal;"&gt;The current treatment reality of major depression underscores the unmet needs that still exist, even 20 years after the availability of the first modern SSRI antidepressant:&lt;/span&gt;&lt;/span&gt;&lt;/div&gt;&lt;div style="direction: ltr; language: en-US; margin-bottom: 0pt; margin-top: 3.24pt; mso-line-break-override: restrictions; punctuation-wrap: simple; text-align: left; unicode-bidi: embed; vertical-align: baseline;"&gt;&lt;span style="color: black; font-family: Arial; font-size: 9.0pt; language: en-US; mso-ascii-font-family: Arial; mso-bidi-font-family: +mn-cs; mso-color-index: 1; mso-fareast-font-family: +mn-ea; mso-font-kerning: 12.0pt;"&gt;&lt;span class="Apple-style-span" style="font-weight: normal;"&gt;&lt;br /&gt;&lt;/span&gt;&lt;/span&gt;&lt;/div&gt;&lt;div style="direction: ltr; language: en-US; margin-bottom: 0pt; margin-top: 3.24pt; mso-line-break-override: restrictions; punctuation-wrap: simple; text-align: left; unicode-bidi: embed; vertical-align: baseline;"&gt;&lt;span style="color: black; font-family: Arial; font-size: 9.0pt; language: en-US; mso-ascii-font-family: Arial; mso-bidi-font-family: +mn-cs; mso-color-index: 1; mso-fareast-font-family: +mn-ea; mso-font-kerning: 12.0pt;"&gt;&lt;span class="Apple-style-span" style="font-weight: normal;"&gt; &lt;/span&gt;&lt;/span&gt;&lt;/div&gt;&lt;div style="direction: ltr; language: en-US; margin-bottom: 0pt; margin-left: .12in; margin-top: 3.24pt; mso-line-break-override: restrictions; punctuation-wrap: simple; text-align: left; text-indent: -.12in; unicode-bidi: embed; vertical-align: baseline;"&gt;&lt;span style="color: black; font-family: Arial; font-size: 9pt; font-style: italic;"&gt;&lt;span class="Apple-style-span" style="font-weight: normal;"&gt;Partial or non-response to first treatment intervention is a common outcome.&lt;/span&gt;&lt;/span&gt;&lt;/div&gt;&lt;div style="direction: ltr; language: en-US; margin-bottom: 0pt; margin-left: .12in; margin-top: 3.24pt; mso-line-break-override: restrictions; punctuation-wrap: simple; text-align: left; text-indent: -.12in; unicode-bidi: embed; vertical-align: baseline;"&gt;&lt;span style="color: black; font-family: Arial; font-size: 9.0pt; language: en-US; mso-ascii-font-family: Arial; mso-bidi-font-family: +mn-cs; mso-color-index: 1; mso-fareast-font-family: +mn-ea; mso-font-kerning: 12.0pt;"&gt;&lt;span class="Apple-style-span" style="font-weight: normal;"&gt;&lt;i&gt;As treatment resistance emerges, the likelihood of future benefit diminishes – &lt;/i&gt;&lt;/span&gt;&lt;/span&gt;&lt;span style="color: black; font-family: Arial; font-size: 9pt;"&gt;&lt;span class="Apple-style-span" style="font-weight: normal;"&gt;&lt;i&gt;this underscores the need to provide safe&lt;/i&gt;&lt;/span&gt;&lt;/span&gt;&lt;/div&gt;&lt;div style="direction: ltr; language: en-US; margin-bottom: 0pt; margin-left: .12in; margin-top: 3.24pt; mso-line-break-override: restrictions; punctuation-wrap: simple; text-align: left; text-indent: -.12in; unicode-bidi: embed; vertical-align: baseline;"&gt;&lt;span style="color: black; font-family: Arial; font-size: 9pt;"&gt;&lt;span class="Apple-style-span" style="font-weight: normal;"&gt;&lt;i&gt;and effective treatment that works, as early as possible in treatment.&lt;/i&gt;&lt;/span&gt;&lt;/span&gt;&lt;/div&gt;&lt;div style="direction: ltr; language: en-US; margin-bottom: 0pt; margin-left: .12in; margin-top: 3.24pt; mso-line-break-override: restrictions; punctuation-wrap: simple; text-align: left; text-indent: -.12in; unicode-bidi: embed; vertical-align: baseline;"&gt;&lt;span style="color: black; font-family: Arial; font-size: 9.0pt; language: en-US; mso-ascii-font-family: Arial; mso-bidi-font-family: +mn-cs; mso-color-index: 1; mso-fareast-font-family: +mn-ea; mso-font-kerning: 12.0pt;"&gt;&lt;span class="Apple-style-span" style="font-weight: normal;"&gt;&lt;i&gt;Despite all available treatments, it is estimated that about 25% of patients will remain refractory to any treatment,&amp;nbsp;&lt;span class="Apple-style-span" style="font-size: 13px; font-style: normal;"&gt;&lt;b&gt;&lt;b&gt;&lt;div style="direction: ltr; display: inline !important; margin-bottom: 0pt; margin-left: 0.12in; margin-top: 3.24pt; text-align: left; text-indent: -0.12in; unicode-bidi: embed; vertical-align: baseline;"&gt;&lt;span style="color: black; font-family: Arial; font-size: 9.0pt; language: en-US; mso-ascii-font-family: Arial; mso-bidi-font-family: +mn-cs; mso-color-index: 1; mso-fareast-font-family: +mn-ea; mso-font-kerning: 12.0pt;"&gt;&lt;i&gt;&lt;span class="Apple-style-span" style="font-size: 13px; font-style: normal;"&gt;&lt;b&gt;&lt;b&gt;&lt;div style="direction: ltr; display: inline !important; margin-bottom: 0pt; margin-left: 0.12in; margin-top: 3.24pt; text-align: left; text-indent: -0.12in; unicode-bidi: embed; vertical-align: baseline;"&gt;&lt;span style="color: black; font-family: Arial; font-size: 9.0pt; language: en-US; mso-ascii-font-family: Arial; mso-bidi-font-family: +mn-cs; mso-color-index: 1; mso-fareast-font-family: +mn-ea; mso-font-kerning: 12.0pt;"&gt;&lt;i&gt;&lt;span class="Apple-style-span" style="font-size: 13px; font-style: normal;"&gt;&lt;b&gt;&lt;b&gt;&lt;div style="direction: ltr; display: inline !important; margin-bottom: 0pt; margin-left: 0.12in; margin-top: 3.24pt; text-align: left; text-indent: -0.12in; unicode-bidi: embed; vertical-align: baseline;"&gt;&lt;span style="color: black; font-family: Arial; font-size: 9.0pt; language: en-US; mso-ascii-font-family: Arial; mso-bidi-font-family: +mn-cs; mso-color-index: 1; mso-fareast-font-family: +mn-ea; mso-font-kerning: 12.0pt;"&gt;&lt;i&gt;&lt;span class="Apple-style-span" style="font-size: 13px; font-style: normal;"&gt;&lt;b&gt;&lt;b&gt;&lt;span class="Apple-style-span" style="font-family: 'Times New Roman'; font-size: medium;"&gt;&lt;b&gt;&lt;b&gt;&lt;div style="direction: ltr; display: inline !important; margin-bottom: 0pt; margin-left: 0.12in; margin-top: 3.24pt; text-align: left; text-indent: -0.12in; unicode-bidi: embed; vertical-align: baseline;"&gt;&lt;span style="color: black; font-family: Arial; font-size: 9pt;"&gt;&lt;i&gt;&lt;span class="Apple-style-span" style="font-size: 13px; font-style: normal;"&gt;&lt;b&gt;&lt;b&gt;&lt;div style="direction: ltr; display: inline !important; margin-bottom: 0pt; margin-left: 0.12in; margin-top: 3.24pt; text-align: left; text-indent: -0.12in; unicode-bidi: embed; vertical-align: baseline;"&gt;&lt;span style="color: black; font-family: Arial; font-size: 9pt;"&gt;&lt;i&gt;&lt;span class="Apple-style-span" style="font-size: 13px; font-style: normal;"&gt;&lt;b&gt;&lt;b&gt;&lt;div style="direction: ltr; display: inline !important; margin-bottom: 0pt; margin-left: 0.12in; margin-top: 3.24pt; text-align: left; text-indent: -0.12in; unicode-bidi: embed; vertical-align: baseline;"&gt;&lt;b&gt;&lt;b&gt;&lt;div style="direction: ltr; display: inline !important; margin-bottom: 0pt; margin-left: 0.12in; margin-top: 3.24pt; text-align: left; text-indent: -0.12in; unicode-bidi: embed; vertical-align: baseline;"&gt;&lt;span style="color: black; font-family: Arial; font-size: 9pt;"&gt;One of the key issues in the treatment of depression is that adverse events and poor tolerability of current treatment options is a major impediment to therapeutic success&lt;/span&gt;&lt;/div&gt;&lt;/b&gt;&lt;/b&gt;&lt;/div&gt;&lt;/b&gt;&lt;/b&gt;&lt;/span&gt;&lt;/i&gt;&lt;/span&gt;&lt;/div&gt;&lt;/b&gt;&lt;/b&gt;&lt;/span&gt;&lt;/i&gt;&lt;/span&gt;&lt;/div&gt;&lt;/b&gt;&lt;/b&gt;&lt;/span&gt;&lt;/b&gt;&lt;/b&gt;&lt;/span&gt;&lt;/i&gt;&lt;/span&gt;&lt;/div&gt;&lt;/b&gt;&lt;/b&gt;&lt;/span&gt;&lt;/i&gt;&lt;/span&gt;&lt;/div&gt;&lt;/b&gt;&lt;/b&gt;&lt;/span&gt;&lt;/i&gt;&lt;/span&gt;&lt;/div&gt;&lt;/b&gt;&lt;/b&gt;&lt;/span&gt;&lt;/i&gt;&lt;/span&gt;&lt;/span&gt;&lt;/div&gt;&lt;div style="direction: ltr; language: en-US; margin-bottom: 0pt; margin-left: .12in; margin-top: 3.24pt; mso-line-break-override: restrictions; punctuation-wrap: simple; text-align: left; text-indent: -.12in; unicode-bidi: embed; vertical-align: baseline;"&gt;&lt;span style="color: black; font-family: Arial; font-size: 9.0pt; language: en-US; mso-ascii-font-family: Arial; mso-bidi-font-family: +mn-cs; mso-color-index: 1; mso-fareast-font-family: +mn-ea; mso-font-kerning: 12.0pt;"&gt;&lt;span class="Apple-style-span" style="font-weight: normal;"&gt;&lt;i&gt;&lt;span class="Apple-style-span" style="font-size: 13px; font-style: normal;"&gt;&lt;b&gt;&lt;b&gt;&lt;div style="direction: ltr; display: inline !important; margin-bottom: 0pt; margin-left: 0.12in; margin-top: 3.24pt; text-align: left; text-indent: -0.12in; unicode-bidi: embed; vertical-align: baseline;"&gt;&lt;span style="color: black; font-family: Arial; font-size: 9.0pt; language: en-US; mso-ascii-font-family: Arial; mso-bidi-font-family: +mn-cs; mso-color-index: 1; mso-fareast-font-family: +mn-ea; mso-font-kerning: 12.0pt;"&gt;&lt;i&gt;&lt;span class="Apple-style-span" style="font-size: 13px; font-style: normal;"&gt;&lt;b&gt;&lt;b&gt;&lt;div style="direction: ltr; display: inline !important; margin-bottom: 0pt; margin-left: 0.12in; margin-top: 3.24pt; text-align: left; text-indent: -0.12in; unicode-bidi: embed; vertical-align: baseline;"&gt;&lt;span style="color: black; font-family: Arial; font-size: 9.0pt; language: en-US; mso-ascii-font-family: Arial; mso-bidi-font-family: +mn-cs; mso-color-index: 1; mso-fareast-font-family: +mn-ea; mso-font-kerning: 12.0pt;"&gt;&lt;i&gt;&lt;span class="Apple-style-span" style="font-size: 13px; font-style: normal;"&gt;&lt;b&gt;&lt;b&gt;&lt;div style="direction: ltr; display: inline !important; margin-bottom: 0pt; margin-left: 0.12in; margin-top: 3.24pt; text-align: left; text-indent: -0.12in; unicode-bidi: embed; vertical-align: baseline;"&gt;&lt;span style="color: black; font-family: Arial; font-size: 9.0pt; language: en-US; mso-ascii-font-family: Arial; mso-bidi-font-family: +mn-cs; mso-color-index: 1; mso-fareast-font-family: +mn-ea; mso-font-kerning: 12.0pt;"&gt;&lt;i&gt;&lt;span class="Apple-style-span" style="font-size: 13px; font-style: normal;"&gt;&lt;b&gt;&lt;b&gt;&lt;span class="Apple-style-span" style="font-family: 'Times New Roman'; font-size: medium;"&gt;&lt;b&gt;&lt;b&gt;&lt;div style="direction: ltr; display: inline !important; margin-bottom: 0pt; margin-left: 0.12in; margin-top: 3.24pt; text-align: left; text-indent: -0.12in; unicode-bidi: embed; vertical-align: baseline;"&gt;&lt;span style="color: black; font-family: Arial; font-size: 9pt;"&gt;&lt;i&gt;&lt;span class="Apple-style-span" style="font-size: 13px; font-style: normal;"&gt;&lt;b&gt;&lt;b&gt;&lt;div style="direction: ltr; display: inline !important; margin-bottom: 0pt; margin-left: 0.12in; margin-top: 3.24pt; text-align: left; text-indent: -0.12in; unicode-bidi: embed; vertical-align: baseline;"&gt;&lt;span style="color: black; font-family: Arial; font-size: 9pt;"&gt;&lt;i&gt;&lt;span class="Apple-style-span" style="font-size: 13px; font-style: normal;"&gt;&lt;b&gt;&lt;b&gt;&lt;div style="direction: ltr; display: inline !important; margin-bottom: 0pt; margin-left: 0.12in; margin-top: 3.24pt; text-align: left; text-indent: -0.12in; unicode-bidi: embed; vertical-align: baseline;"&gt;&lt;b&gt;&lt;b&gt;&lt;div style="direction: ltr; display: inline !important; margin-bottom: 0pt; margin-left: 0.12in; margin-top: 3.24pt; text-align: left; text-indent: -0.12in; unicode-bidi: embed; vertical-align: baseline;"&gt;&lt;span style="color: black; font-family: Arial; font-size: 9pt;"&gt;&lt;div class="O2" style="direction: ltr; language: en-US; line-height: 95%; margin-bottom: 0pt; margin-left: .5in; margin-top: 3.6pt; mso-line-break-override: none; punctuation-wrap: hanging; text-align: left; text-indent: -.12in; unicode-bidi: embed; vertical-align: baseline;"&gt;&lt;span style="color: black; font-family: Arial; font-size: 10.0pt; language: fr; mso-ascii-font-family: Arial; mso-bidi-font-family: +mn-cs; mso-color-index: 1; mso-fareast-font-family: +mn-ea; mso-font-kerning: 12.0pt;"&gt;&lt;span class="Apple-style-span" style="font-weight: normal;"&gt;There are &lt;/span&gt;&lt;/span&gt;&lt;span style="color: black; font-family: Arial; font-size: 10.0pt; language: fr; mso-ascii-font-family: Arial; mso-bidi-font-family: +mn-cs; mso-color-index: 1; mso-fareast-font-family: +mn-ea; mso-font-kerning: 12.0pt;"&gt;&lt;span class="Apple-style-span" style="font-weight: normal;"&gt;many&lt;/span&gt;&lt;/span&gt;&lt;span style="color: black; font-family: Arial; font-size: 10.0pt; language: fr; mso-ascii-font-family: Arial; mso-bidi-font-family: +mn-cs; mso-color-index: 1; mso-fareast-font-family: +mn-ea; mso-font-kerning: 12.0pt;"&gt;&lt;span class="Apple-style-span" style="font-weight: normal;"&gt; &lt;/span&gt;&lt;/span&gt;&lt;span style="color: black; font-family: Arial; font-size: 10.0pt; language: fr; mso-ascii-font-family: Arial; mso-bidi-font-family: +mn-cs; mso-color-index: 1; mso-fareast-font-family: +mn-ea; mso-font-kerning: 12.0pt;"&gt;&lt;span class="Apple-style-span" style="font-weight: normal;"&gt;reasons&lt;/span&gt;&lt;/span&gt;&lt;span style="color: black; font-family: Arial; font-size: 10.0pt; language: fr; mso-ascii-font-family: Arial; mso-bidi-font-family: +mn-cs; mso-color-index: 1; mso-fareast-font-family: +mn-ea; mso-font-kerning: 12.0pt;"&gt;&lt;span class="Apple-style-span" style="font-weight: normal;"&gt; &lt;/span&gt;&lt;/span&gt;&lt;span style="color: black; font-family: Arial; font-size: 10.0pt; language: fr; mso-ascii-font-family: Arial; mso-bidi-font-family: +mn-cs; mso-color-index: 1; mso-fareast-font-family: +mn-ea; mso-font-kerning: 12.0pt;"&gt;&lt;span class="Apple-style-span" style="font-weight: normal;"&gt;why&lt;/span&gt;&lt;/span&gt;&lt;span style="color: black; font-family: Arial; font-size: 10.0pt; language: fr; mso-ascii-font-family: Arial; mso-bidi-font-family: +mn-cs; mso-color-index: 1; mso-fareast-font-family: +mn-ea; mso-font-kerning: 12.0pt;"&gt;&lt;span class="Apple-style-span" style="font-weight: normal;"&gt; patients &lt;/span&gt;&lt;/span&gt;&lt;span style="color: black; font-family: Arial; font-size: 10.0pt; language: fr; mso-ascii-font-family: Arial; mso-bidi-font-family: +mn-cs; mso-color-index: 1; mso-fareast-font-family: +mn-ea; mso-font-kerning: 12.0pt;"&gt;&lt;span class="Apple-style-span" style="font-weight: normal;"&gt;may not&amp;nbsp;&lt;/span&gt;&lt;/span&gt;&lt;span style="color: black; font-family: Arial; font-size: 10.0pt; language: fr; mso-ascii-font-family: Arial; mso-bidi-font-family: +mn-cs; mso-color-index: 1; mso-fareast-font-family: +mn-ea; mso-font-kerning: 12.0pt;"&gt;&lt;span class="Apple-style-span" style="font-weight: normal;"&gt;continue the&amp;nbsp;&lt;/span&gt;&lt;/span&gt;&lt;span style="color: black; font-family: Arial; font-size: 10.0pt; language: fr; mso-ascii-font-family: Arial; mso-bidi-font-family: +mn-cs; mso-color-index: 1; mso-fareast-font-family: +mn-ea; mso-font-kerning: 12.0pt;"&gt;&lt;span class="Apple-style-span" style="font-weight: normal;"&gt;prescribed&lt;/span&gt;&lt;/span&gt;&lt;span style="color: black; font-family: Arial; font-size: 10.0pt; language: fr; mso-ascii-font-family: Arial; mso-bidi-font-family: +mn-cs; mso-color-index: 1; mso-fareast-font-family: +mn-ea; mso-font-kerning: 12.0pt;"&gt;&lt;span class="Apple-style-span" style="font-weight: normal;"&gt; &lt;/span&gt;&lt;/span&gt;&lt;span style="color: black; font-family: Arial; font-size: 10.0pt; language: fr; mso-ascii-font-family: Arial; mso-bidi-font-family: +mn-cs; mso-color-index: 1; mso-fareast-font-family: +mn-ea; mso-font-kerning: 12.0pt;"&gt;&lt;span class="Apple-style-span" style="font-weight: normal;"&gt;treatment, among the most important&lt;/span&gt;&lt;/span&gt;&lt;span style="color: black; font-family: Arial; font-size: 10.0pt; language: fr; mso-ascii-font-family: Arial; mso-bidi-font-family: +mn-cs; mso-color-index: 1; mso-fareast-font-family: +mn-ea; mso-font-kerning: 12.0pt;"&gt;&lt;span class="Apple-style-span" style="font-weight: normal;"&gt;:&lt;/span&gt;&lt;/span&gt;&lt;/div&gt;&lt;div class="O3" style="direction: ltr; language: en-US; line-height: 95%; margin-bottom: 0pt; margin-left: .75in; margin-top: 3.6pt; mso-line-break-override: none; punctuation-wrap: hanging; text-align: left; text-indent: -.12in; unicode-bidi: embed; vertical-align: baseline;"&gt;&lt;span style="font-size: 10.0pt;"&gt;&lt;span class="Apple-style-span" style="font-weight: normal;"&gt;•&lt;/span&gt;&lt;/span&gt;&lt;span style="color: black; font-family: Arial; font-size: 10.0pt; language: fr; mso-ascii-font-family: Arial; mso-bidi-font-family: +mn-cs; mso-color-index: 1; mso-fareast-font-family: +mn-ea; mso-font-kerning: 12.0pt;"&gt;&lt;span class="Apple-style-span" style="font-weight: normal;"&gt;Adverse &lt;/span&gt;&lt;/span&gt;&lt;span style="color: black; font-family: Arial; font-size: 10.0pt; language: fr; mso-ascii-font-family: Arial; mso-bidi-font-family: +mn-cs; mso-color-index: 1; mso-fareast-font-family: +mn-ea; mso-font-kerning: 12.0pt;"&gt;&lt;span class="Apple-style-span" style="font-weight: normal;"&gt;effects&lt;/span&gt;&lt;/span&gt;&lt;span style="color: black; font-family: Arial; font-size: 10.0pt; language: fr; mso-ascii-font-family: Arial; mso-bidi-font-family: +mn-cs; mso-color-index: 1; mso-fareast-font-family: +mn-ea; mso-font-kerning: 12.0pt;"&gt;&lt;span class="Apple-style-span" style="font-weight: normal;"&gt; &lt;/span&gt;&lt;/span&gt;&lt;/div&gt;&lt;div class="O3" style="direction: ltr; language: en-US; line-height: 95%; margin-bottom: 0pt; margin-left: .75in; margin-top: 3.6pt; mso-line-break-override: none; punctuation-wrap: hanging; text-align: left; text-indent: -.12in; unicode-bidi: embed; vertical-align: baseline;"&gt;&lt;span style="font-size: 10.0pt;"&gt;&lt;span class="Apple-style-span" style="font-weight: normal;"&gt;•&lt;/span&gt;&lt;/span&gt;&lt;span style="color: black; font-family: Arial; font-size: 10.0pt; language: fr; mso-ascii-font-family: Arial; mso-bidi-font-family: +mn-cs; mso-color-index: 1; mso-fareast-font-family: +mn-ea; mso-font-kerning: 12.0pt;"&gt;&lt;span class="Apple-style-span" style="font-weight: normal;"&gt;Patients &lt;/span&gt;&lt;/span&gt;&lt;span style="color: black; font-family: Arial; font-size: 10.0pt; language: fr; mso-ascii-font-family: Arial; mso-bidi-font-family: +mn-cs; mso-color-index: 1; mso-fareast-font-family: +mn-ea; mso-font-kerning: 12.0pt;"&gt;&lt;span class="Apple-style-span" style="font-weight: normal;"&gt;may&lt;/span&gt;&lt;/span&gt;&lt;span style="color: black; font-family: Arial; font-size: 10.0pt; language: fr; mso-ascii-font-family: Arial; mso-bidi-font-family: +mn-cs; mso-color-index: 1; mso-fareast-font-family: +mn-ea; mso-font-kerning: 12.0pt;"&gt;&lt;span class="Apple-style-span" style="font-weight: normal;"&gt; &lt;/span&gt;&lt;/span&gt;&lt;span style="color: black; font-family: Arial; font-size: 10.0pt; language: fr; mso-ascii-font-family: Arial; mso-bidi-font-family: +mn-cs; mso-color-index: 1; mso-fareast-font-family: +mn-ea; mso-font-kerning: 12.0pt;"&gt;&lt;span class="Apple-style-span" style="font-weight: normal;"&gt;begin&lt;/span&gt;&lt;/span&gt;&lt;span style="color: black; font-family: Arial; font-size: 10.0pt; language: fr; mso-ascii-font-family: Arial; mso-bidi-font-family: +mn-cs; mso-color-index: 1; mso-fareast-font-family: +mn-ea; mso-font-kerning: 12.0pt;"&gt;&lt;span class="Apple-style-span" style="font-weight: normal;"&gt; to &lt;/span&gt;&lt;/span&gt;&lt;span style="color: black; font-family: Arial; font-size: 10.0pt; language: fr; mso-ascii-font-family: Arial; mso-bidi-font-family: +mn-cs; mso-color-index: 1; mso-fareast-font-family: +mn-ea; mso-font-kerning: 12.0pt;"&gt;&lt;span class="Apple-style-span" style="font-weight: normal;"&gt;feel&lt;/span&gt;&lt;/span&gt;&lt;span style="color: black; font-family: Arial; font-size: 10.0pt; language: fr; mso-ascii-font-family: Arial; mso-bidi-font-family: +mn-cs; mso-color-index: 1; mso-fareast-font-family: +mn-ea; mso-font-kerning: 12.0pt;"&gt;&lt;span class="Apple-style-span" style="font-weight: normal;"&gt; &lt;/span&gt;&lt;/span&gt;&lt;span style="color: black; font-family: Arial; font-size: 10.0pt; language: fr; mso-ascii-font-family: Arial; mso-bidi-font-family: +mn-cs; mso-color-index: 1; mso-fareast-font-family: +mn-ea; mso-font-kerning: 12.0pt;"&gt;&lt;span class="Apple-style-span" style="font-weight: normal;"&gt;better&lt;/span&gt;&lt;/span&gt;&lt;span style="color: black; font-family: Arial; font-size: 10.0pt; language: fr; mso-ascii-font-family: Arial; mso-bidi-font-family: +mn-cs; mso-color-index: 1; mso-fareast-font-family: +mn-ea; mso-font-kerning: 12.0pt;"&gt;&lt;span class="Apple-style-span" style="font-weight: normal;"&gt; and &lt;/span&gt;&lt;/span&gt;&lt;span style="color: black; font-family: Arial; font-size: 10.0pt; language: fr; mso-ascii-font-family: Arial; mso-bidi-font-family: +mn-cs; mso-color-index: 1; mso-fareast-font-family: +mn-ea; mso-font-kerning: 12.0pt;"&gt;&lt;span class="Apple-style-span" style="font-weight: normal;"&gt;decide&lt;/span&gt;&lt;/span&gt;&lt;span style="color: black; font-family: Arial; font-size: 10.0pt; language: fr; mso-ascii-font-family: Arial; mso-bidi-font-family: +mn-cs; mso-color-index: 1; mso-fareast-font-family: +mn-ea; mso-font-kerning: 12.0pt;"&gt;&lt;span class="Apple-style-span" style="font-weight: normal;"&gt; &lt;/span&gt;&lt;/span&gt;&lt;span style="color: black; font-family: Arial; font-size: 10.0pt; language: fr; mso-ascii-font-family: Arial; mso-bidi-font-family: +mn-cs; mso-color-index: 1; mso-fareast-font-family: +mn-ea; mso-font-kerning: 12.0pt;"&gt;&lt;span class="Apple-style-span" style="font-weight: normal;"&gt;they&lt;/span&gt;&lt;/span&gt;&lt;span style="color: black; font-family: Arial; font-size: 10.0pt; language: fr; mso-ascii-font-family: Arial; mso-bidi-font-family: +mn-cs; mso-color-index: 1; mso-fareast-font-family: +mn-ea; mso-font-kerning: 12.0pt;"&gt;&lt;span class="Apple-style-span" style="font-weight: normal;"&gt; no longer &lt;/span&gt;&lt;/span&gt;&lt;span style="color: black; font-family: Arial; font-size: 10.0pt; language: fr; mso-ascii-font-family: Arial; mso-bidi-font-family: +mn-cs; mso-color-index: 1; mso-fareast-font-family: +mn-ea; mso-font-kerning: 12.0pt;"&gt;&lt;span class="Apple-style-span" style="font-weight: normal;"&gt;need&lt;/span&gt;&lt;/span&gt;&lt;span style="color: black; font-family: Arial; font-size: 10.0pt; language: fr; mso-ascii-font-family: Arial; mso-bidi-font-family: +mn-cs; mso-color-index: 1; mso-fareast-font-family: +mn-ea; mso-font-kerning: 12.0pt;"&gt;&lt;span class="Apple-style-span" style="font-weight: normal;"&gt; &lt;/span&gt;&lt;/span&gt;&lt;span style="color: black; font-family: Arial; font-size: 10.0pt; language: fr; mso-ascii-font-family: Arial; mso-bidi-font-family: +mn-cs; mso-color-index: 1; mso-fareast-font-family: +mn-ea; mso-font-kerning: 12.0pt;"&gt;&lt;span class="Apple-style-span" style="font-weight: normal;"&gt;treatment&lt;/span&gt;&lt;/span&gt;&lt;span style="color: black; font-family: Arial; font-size: 10.0pt; language: fr; mso-ascii-font-family: Arial; mso-bidi-font-family: +mn-cs; mso-color-index: 1; mso-fareast-font-family: +mn-ea; mso-font-kerning: 12.0pt;"&gt;&lt;span class="Apple-style-span" style="font-weight: normal;"&gt; &lt;/span&gt;&lt;/span&gt;&lt;/div&gt;&lt;div class="O3" style="direction: ltr; language: en-US; line-height: 95%; margin-bottom: 0pt; margin-left: .75in; margin-top: 3.6pt; mso-line-break-override: none; punctuation-wrap: hanging; text-align: left; text-indent: -.12in; unicode-bidi: embed; vertical-align: baseline;"&gt;&lt;span style="font-size: 10.0pt;"&gt;&lt;span class="Apple-style-span" style="font-weight: normal;"&gt;•&lt;/span&gt;&lt;/span&gt;&lt;span style="color: black; font-family: Arial; font-size: 10.0pt; language: fr; mso-ascii-font-family: Arial; mso-bidi-font-family: +mn-cs; mso-color-index: 1; mso-fareast-font-family: +mn-ea; mso-font-kerning: 12.0pt;"&gt;&lt;span class="Apple-style-span" style="font-weight: normal;"&gt;Regimen&lt;/span&gt;&lt;/span&gt;&lt;span style="color: black; font-family: Arial; font-size: 10.0pt; language: fr; mso-ascii-font-family: Arial; mso-bidi-font-family: +mn-cs; mso-color-index: 1; mso-fareast-font-family: +mn-ea; mso-font-kerning: 12.0pt;"&gt;&lt;span class="Apple-style-span" style="font-weight: normal;"&gt; &lt;/span&gt;&lt;/span&gt;&lt;span style="color: black; font-family: Arial; font-size: 10.0pt; language: fr; mso-ascii-font-family: Arial; mso-bidi-font-family: +mn-cs; mso-color-index: 1; mso-fareast-font-family: +mn-ea; mso-font-kerning: 12.0pt;"&gt;&lt;span class="Apple-style-span" style="font-weight: normal;"&gt;may&lt;/span&gt;&lt;/span&gt;&lt;span style="color: black; font-family: Arial; font-size: 10.0pt; language: fr; mso-ascii-font-family: Arial; mso-bidi-font-family: +mn-cs; mso-color-index: 1; mso-fareast-font-family: +mn-ea; mso-font-kerning: 12.0pt;"&gt;&lt;span class="Apple-style-span" style="font-weight: normal;"&gt; &lt;/span&gt;&lt;/span&gt;&lt;span style="color: black; font-family: Arial; font-size: 10.0pt; language: fr; mso-ascii-font-family: Arial; mso-bidi-font-family: +mn-cs; mso-color-index: 1; mso-fareast-font-family: +mn-ea; mso-font-kerning: 12.0pt;"&gt;&lt;span class="Apple-style-span" style="font-weight: normal;"&gt;be&lt;/span&gt;&lt;/span&gt;&lt;span style="color: black; font-family: Arial; font-size: 10.0pt; language: fr; mso-ascii-font-family: Arial; mso-bidi-font-family: +mn-cs; mso-color-index: 1; mso-fareast-font-family: +mn-ea; mso-font-kerning: 12.0pt;"&gt;&lt;span class="Apple-style-span" style="font-weight: normal;"&gt; &lt;/span&gt;&lt;/span&gt;&lt;span style="color: black; font-family: Arial; font-size: 10.0pt; language: fr; mso-ascii-font-family: Arial; mso-bidi-font-family: +mn-cs; mso-color-index: 1; mso-fareast-font-family: +mn-ea; mso-font-kerning: 12.0pt;"&gt;&lt;span class="Apple-style-span" style="font-weight: normal;"&gt;too&lt;/span&gt;&lt;/span&gt;&lt;span style="color: black; font-family: Arial; font-size: 10.0pt; language: fr; mso-ascii-font-family: Arial; mso-bidi-font-family: +mn-cs; mso-color-index: 1; mso-fareast-font-family: +mn-ea; mso-font-kerning: 12.0pt;"&gt;&lt;span class="Apple-style-span" style="font-weight: normal;"&gt; &lt;/span&gt;&lt;/span&gt;&lt;span style="color: black; font-family: Arial; font-size: 10.0pt; language: fr; mso-ascii-font-family: Arial; mso-bidi-font-family: +mn-cs; mso-color-index: 1; mso-fareast-font-family: +mn-ea; mso-font-kerning: 12.0pt;"&gt;&lt;span class="Apple-style-span" style="font-weight: normal;"&gt;complex&lt;/span&gt;&lt;/span&gt;&lt;span style="color: black; font-family: Arial; font-size: 10.0pt; language: fr; mso-ascii-font-family: Arial; mso-bidi-font-family: +mn-cs; mso-color-index: 1; mso-fareast-font-family: +mn-ea; mso-font-kerning: 12.0pt;"&gt;&lt;span class="Apple-style-span" style="font-weight: normal;"&gt; &lt;/span&gt;&lt;/span&gt;&lt;/div&gt;&lt;div class="O3" style="direction: ltr; language: en-US; line-height: 95%; margin-bottom: 0pt; margin-left: .75in; margin-top: 3.6pt; mso-line-break-override: none; punctuation-wrap: hanging; text-align: left; text-indent: -.12in; unicode-bidi: embed; vertical-align: baseline;"&gt;&lt;span style="font-size: 10.0pt;"&gt;&lt;span class="Apple-style-span" style="font-weight: normal;"&gt;•&lt;/span&gt;&lt;/span&gt;&lt;span style="color: black; font-family: Arial; font-size: 10.0pt; language: fr; mso-ascii-font-family: Arial; mso-bidi-font-family: +mn-cs; mso-color-index: 1; mso-fareast-font-family: +mn-ea; mso-font-kerning: 12.0pt;"&gt;&lt;span class="Apple-style-span" style="font-weight: normal;"&gt;Patient’s&lt;/span&gt;&lt;/span&gt;&lt;span style="color: black; font-family: Arial; font-size: 10.0pt; language: fr; mso-ascii-font-family: Arial; mso-bidi-font-family: +mn-cs; mso-color-index: 1; mso-fareast-font-family: +mn-ea; mso-font-kerning: 12.0pt;"&gt;&lt;span class="Apple-style-span" style="font-weight: normal;"&gt; &lt;/span&gt;&lt;/span&gt;&lt;span style="color: black; font-family: Arial; font-size: 10.0pt; language: fr; mso-ascii-font-family: Arial; mso-bidi-font-family: +mn-cs; mso-color-index: 1; mso-fareast-font-family: +mn-ea; mso-font-kerning: 12.0pt;"&gt;&lt;span class="Apple-style-span" style="font-weight: normal;"&gt;memory&lt;/span&gt;&lt;/span&gt;&lt;span style="color: black; font-family: Arial; font-size: 10.0pt; language: fr; mso-ascii-font-family: Arial; mso-bidi-font-family: +mn-cs; mso-color-index: 1; mso-fareast-font-family: +mn-ea; mso-font-kerning: 12.0pt;"&gt;&lt;span class="Apple-style-span" style="font-weight: normal;"&gt; &lt;/span&gt;&lt;/span&gt;&lt;span style="color: black; font-family: Arial; font-size: 10.0pt; language: fr; mso-ascii-font-family: Arial; mso-bidi-font-family: +mn-cs; mso-color-index: 1; mso-fareast-font-family: +mn-ea; mso-font-kerning: 12.0pt;"&gt;&lt;span class="Apple-style-span" style="font-weight: normal;"&gt;may&lt;/span&gt;&lt;/span&gt;&lt;span style="color: black; font-family: Arial; font-size: 10.0pt; language: fr; mso-ascii-font-family: Arial; mso-bidi-font-family: +mn-cs; mso-color-index: 1; mso-fareast-font-family: +mn-ea; mso-font-kerning: 12.0pt;"&gt;&lt;span class="Apple-style-span" style="font-weight: normal;"&gt; &lt;/span&gt;&lt;/span&gt;&lt;span style="color: black; font-family: Arial; font-size: 10.0pt; language: fr; mso-ascii-font-family: Arial; mso-bidi-font-family: +mn-cs; mso-color-index: 1; mso-fareast-font-family: +mn-ea; mso-font-kerning: 12.0pt;"&gt;&lt;span class="Apple-style-span" style="font-weight: normal;"&gt;be&lt;/span&gt;&lt;/span&gt;&lt;span style="color: black; font-family: Arial; font-size: 10.0pt; language: fr; mso-ascii-font-family: Arial; mso-bidi-font-family: +mn-cs; mso-color-index: 1; mso-fareast-font-family: +mn-ea; mso-font-kerning: 12.0pt;"&gt;&lt;span class="Apple-style-span" style="font-weight: normal;"&gt; &lt;/span&gt;&lt;/span&gt;&lt;span style="color: black; font-family: Arial; font-size: 10.0pt; language: fr; mso-ascii-font-family: Arial; mso-bidi-font-family: +mn-cs; mso-color-index: 1; mso-fareast-font-family: +mn-ea; mso-font-kerning: 12.0pt;"&gt;&lt;span class="Apple-style-span" style="font-weight: normal;"&gt;affected&lt;/span&gt;&lt;/span&gt;&lt;span style="color: black; font-family: Arial; font-size: 10.0pt; language: fr; mso-ascii-font-family: Arial; mso-bidi-font-family: +mn-cs; mso-color-index: 1; mso-fareast-font-family: +mn-ea; mso-font-kerning: 12.0pt;"&gt;&lt;span class="Apple-style-span" style="font-weight: normal;"&gt; by MDD&lt;/span&gt;&lt;/span&gt;&lt;/div&gt;&lt;div class="O3" style="direction: ltr; language: en-US; line-height: 95%; margin-bottom: 0pt; margin-left: .75in; margin-top: 3.6pt; mso-line-break-override: none; punctuation-wrap: hanging; text-align: left; text-indent: -.12in; unicode-bidi: embed; vertical-align: baseline;"&gt;&lt;span class="Apple-style-span" style="font-size: small;"&gt;&lt;span class="Apple-style-span" style="font-size: 13px; font-weight: normal;"&gt;&lt;br /&gt;&lt;/span&gt;&lt;/span&gt;&lt;/div&gt;&lt;div class="O3" style="direction: ltr; language: en-US; line-height: 95%; margin-bottom: 0pt; margin-left: .75in; margin-top: 3.6pt; mso-line-break-override: none; punctuation-wrap: hanging; text-align: left; text-indent: -.12in; unicode-bidi: embed; vertical-align: baseline;"&gt;&lt;span class="Apple-style-span" style="font-size: small;"&gt;&lt;span class="Apple-style-span" style="font-size: 13px; font-weight: normal;"&gt;&lt;div style="direction: ltr; language: en-US; margin-bottom: 0pt; margin-top: 3.6pt; mso-line-break-override: restrictions; punctuation-wrap: simple; text-align: left; unicode-bidi: embed; vertical-align: baseline;"&gt;Treatment resistance translates into:&lt;/div&gt;&lt;div class="O1" style="direction: ltr; language: en-US; margin-bottom: 0pt; margin-left: .5in; margin-top: 3.6pt; mso-line-break-override: restrictions; punctuation-wrap: simple; text-align: left; text-indent: -.31in; unicode-bidi: embed; vertical-align: baseline;"&gt;&lt;span style="font-size: 10.0pt;"&gt;&lt;span style="font-family: Arial; mso-special-format: bullet;"&gt;•&lt;/span&gt;&lt;/span&gt;&lt;span style="color: black; font-family: Arial; font-size: 10.0pt; language: en-US; mso-ascii-font-family: Arial; mso-bidi-font-family: +mn-cs; mso-color-index: 1; mso-fareast-font-family: +mn-ea; mso-font-kerning: 12.0pt;"&gt; Patients experience significantly more inpatient hospitalizations, outpatient office visits and use more and costlier psychotropic medications,&lt;/span&gt;&lt;/div&gt;&lt;div class="O1" style="direction: ltr; language: en-US; margin-bottom: 0pt; margin-left: .5in; margin-top: 3.6pt; mso-line-break-override: restrictions; punctuation-wrap: simple; text-align: left; text-indent: -.31in; unicode-bidi: embed; vertical-align: baseline;"&gt;&lt;span style="font-size: 10.0pt;"&gt;&lt;span style="font-family: Arial; mso-special-format: bullet;"&gt;•&lt;/span&gt;&lt;/span&gt;&lt;span style="color: black; font-family: Arial; font-size: 10.0pt; language: en-US; mso-ascii-font-family: Arial; mso-bidi-font-family: +mn-cs; mso-color-index: 1; mso-fareast-font-family: +mn-ea; mso-font-kerning: 12.0pt;"&gt; The health care costs, on average, range from 2 to 6 times the costs for a non-treatment resistant patient,&lt;/span&gt;&lt;/div&gt;&lt;div class="O1" style="direction: ltr; language: en-US; margin-bottom: 0pt; margin-left: .5in; margin-top: 3.6pt; mso-line-break-override: restrictions; punctuation-wrap: simple; text-align: left; text-indent: -.31in; unicode-bidi: embed; vertical-align: baseline;"&gt;&lt;span style="font-size: 10.0pt;"&gt;&lt;span style="font-family: Arial; mso-special-format: bullet;"&gt;•&lt;/span&gt;&lt;/span&gt;&lt;span style="color: black; font-family: Arial; font-size: 10.0pt; language: en-US; mso-ascii-font-family: Arial; mso-bidi-font-family: +mn-cs; mso-color-index: 1; mso-fareast-font-family: +mn-ea; mso-font-kerning: 12.0pt;"&gt; For example, one report estimated that the mean total medical costs in a population of hospitalized treatment resistant patients were in excess of $42,000 compared to only $6,500 for a comparison group of non-treatment resistant patients,&lt;/span&gt;&lt;/div&gt;&lt;div class="O1" style="direction: ltr; language: en-US; margin-bottom: 0pt; margin-left: .5in; margin-top: 3.6pt; mso-line-break-override: restrictions; punctuation-wrap: simple; text-align: left; text-indent: -.31in; unicode-bidi: embed; vertical-align: baseline;"&gt;&lt;span style="font-size: 10.0pt;"&gt;&lt;span style="font-family: Arial; mso-special-format: bullet;"&gt;•&lt;/span&gt;&lt;/span&gt;&lt;span style="color: black; font-family: Arial; font-size: 10.0pt; language: en-US; mso-ascii-font-family: Arial; mso-bidi-font-family: +mn-cs; mso-color-index: 1; mso-fareast-font-family: +mn-ea; mso-font-kerning: 12.0pt;"&gt; The economic costs are also seen in the workplace (&lt;/span&gt;&lt;span style="color: black; font-family: Arial; font-size: 10.0pt; language: en-US; mso-ascii-font-family: Arial; mso-bidi-font-family: +mn-cs; mso-color-index: 1; mso-fareast-font-family: +mn-ea; mso-font-kerning: 12.0pt;"&gt;ie&lt;/span&gt;&lt;span style="color: black; font-family: Arial; font-size: 10.0pt; language: en-US; mso-ascii-font-family: Arial; mso-bidi-font-family: +mn-cs; mso-color-index: 1; mso-fareast-font-family: +mn-ea; mso-font-kerning: 12.0pt;"&gt;. increased disability and absenteeism), and in an increased utilization of health care services for non-psychiatric conditions.&lt;/span&gt;&lt;/div&gt;&lt;/span&gt;&lt;/span&gt;&lt;/div&gt;&lt;span class="Apple-style-span" style="font-size: small;"&gt;&lt;span class="Apple-style-span" style="font-size: 13px;"&gt;&lt;br /&gt;&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;/div&gt;&lt;/b&gt;&lt;/b&gt;&lt;/div&gt;&lt;/b&gt;&lt;/b&gt;&lt;/span&gt;&lt;/i&gt;&lt;/span&gt;&lt;/div&gt;&lt;/b&gt;&lt;/b&gt;&lt;/span&gt;&lt;/i&gt;&lt;/span&gt;&lt;/div&gt;&lt;/b&gt;&lt;/b&gt;&lt;/span&gt;&lt;/b&gt;&lt;/b&gt;&lt;/span&gt;&lt;/i&gt;&lt;/span&gt;&lt;/div&gt;&lt;/b&gt;&lt;/b&gt;&lt;/span&gt;&lt;/i&gt;&lt;/span&gt;&lt;/div&gt;&lt;/b&gt;&lt;/b&gt;&lt;/span&gt;&lt;/i&gt;&lt;/span&gt;&lt;/div&gt;&lt;/b&gt;&lt;/b&gt;&lt;/span&gt;&lt;/i&gt;&lt;/span&gt;&lt;/span&gt;&lt;/div&gt;&lt;span class="Apple-style-span" style="font-family: 'Times New Roman'; font-size: medium;"&gt;&lt;div style="direction: ltr; margin-bottom: 0pt; margin-left: 0px; margin-right: 0px; margin-top: 4.2pt; text-align: left; unicode-bidi: embed; vertical-align: baseline;"&gt;&lt;span style="color: black; font-family: Arial; font-size: 10pt;"&gt;&lt;b&gt;&lt;/b&gt;&lt;/span&gt;&lt;/div&gt;&lt;/span&gt;&lt;br /&gt;&lt;div style="direction: ltr; margin-bottom: 0pt; margin-left: 0px; margin-right: 0px; margin-top: 4.2pt; text-align: left; unicode-bidi: embed; vertical-align: baseline;"&gt;&lt;span style="color: black; font-family: Arial; font-size: 10pt;"&gt;&lt;/span&gt;&lt;/div&gt;&lt;div style="direction: ltr; margin-bottom: 0pt; margin-left: 0px; margin-right: 0px; margin-top: 4.2pt; text-align: left; unicode-bidi: embed; vertical-align: baseline;"&gt;&lt;span style="color: black; font-family: Arial; font-size: 10pt;"&gt;&lt;/span&gt;&lt;/div&gt;&lt;div style="direction: ltr; language: en-US; margin-bottom: 0pt; margin-left: .12in; margin-top: 3.24pt; mso-line-break-override: restrictions; punctuation-wrap: simple; text-align: left; text-indent: -.12in; unicode-bidi: embed; vertical-align: baseline;"&gt;&lt;span style="color: black; font-family: Arial; font-size: 9.0pt; language: en-US; mso-ascii-font-family: Arial; mso-bidi-font-family: +mn-cs; mso-color-index: 1; mso-fareast-font-family: +mn-ea; mso-font-kerning: 12.0pt;"&gt;&lt;span class="Apple-style-span" style="font-weight: normal;"&gt;&lt;i&gt;&lt;span class="Apple-style-span" style="font-size: 13px; font-style: normal;"&gt;&lt;b&gt;&lt;span class="Apple-style-span" style="font-weight: normal;"&gt;&lt;b&gt;&lt;div style="direction: ltr; display: inline !important; margin-bottom: 0pt; margin-left: 0.12in; margin-top: 3.24pt; text-align: left; text-indent: -0.12in; unicode-bidi: embed; vertical-align: baseline;"&gt;&lt;span style="color: black; font-family: Arial; font-size: 9.0pt; language: en-US; mso-ascii-font-family: Arial; mso-bidi-font-family: +mn-cs; mso-color-index: 1; mso-fareast-font-family: +mn-ea; mso-font-kerning: 12.0pt;"&gt;&lt;span class="Apple-style-span" style="font-weight: normal;"&gt;&lt;i&gt;&lt;span class="Apple-style-span" style="font-size: 13px; font-style: normal;"&gt;&lt;b&gt;&lt;span class="Apple-style-span" style="font-weight: normal;"&gt;&lt;b&gt;&lt;div style="direction: ltr; display: inline !important; margin-bottom: 0pt; margin-left: 0.12in; margin-top: 3.24pt; text-align: left; text-indent: -0.12in; unicode-bidi: embed; vertical-align: baseline;"&gt;&lt;span class="Apple-style-span" style="font-weight: normal;"&gt;&lt;b&gt;&lt;span class="Apple-style-span" style="font-weight: normal;"&gt;&lt;b&gt;&lt;div style="direction: ltr; display: inline !important; margin-bottom: 0pt; margin-left: 0.12in; margin-top: 3.24pt; text-align: left; text-indent: -0.12in; unicode-bidi: embed; vertical-align: baseline;"&gt;&lt;span style="color: black; font-family: Arial; font-size: 9.0pt; language: en-US; mso-ascii-font-family: Arial; mso-bidi-font-family: +mn-cs; mso-color-index: 1; mso-fareast-font-family: +mn-ea; mso-font-kerning: 12.0pt;"&gt;&lt;span class="Apple-style-span" style="font-weight: normal;"&gt;&lt;br /&gt;&lt;/span&gt;&lt;/span&gt;&lt;/div&gt;&lt;/b&gt;&lt;/span&gt;&lt;/b&gt;&lt;/span&gt;&lt;/div&gt;&lt;/b&gt;&lt;/span&gt;&lt;/b&gt;&lt;/span&gt;&lt;/i&gt;&lt;/span&gt;&lt;/span&gt;&lt;/div&gt;&lt;/b&gt;&lt;/span&gt;&lt;/b&gt;&lt;/span&gt;&lt;/i&gt;&lt;/span&gt;&lt;/span&gt;&lt;/div&gt;&lt;div style="direction: ltr; language: en-US; margin-bottom: 0pt; margin-left: .12in; margin-top: 3.24pt; mso-line-break-override: restrictions; punctuation-wrap: simple; text-align: left; text-indent: -.12in; unicode-bidi: embed; vertical-align: baseline;"&gt;&lt;span class="Apple-style-span" style="font-weight: normal;"&gt;&lt;span class="Apple-style-span" style="font-size: small;"&gt;&lt;span class="Apple-style-span" style="font-size: 12px;"&gt;&lt;br /&gt;&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;/div&gt;&lt;/b&gt;&lt;/b&gt;&lt;div class="blogger-post-footer"&gt;&lt;img width='1' height='1' src='https://blogger.googleusercontent.com/tracker/5823906349768938190-1468638523833546462?l=chandlertms.blogspot.com' alt='' /&gt;&lt;/div&gt;</content><link rel='replies' type='application/atom+xml' href='http://chandlertms.blogspot.com/feeds/1468638523833546462/comments/default' title='Post Comments'/><link rel='replies' type='text/html' href='http://chandlertms.blogspot.com/2010/04/is-tms-needed.html#comment-form' title='0 Comments'/><link rel='edit' type='application/atom+xml' href='http://www.blogger.com/feeds/5823906349768938190/posts/default/1468638523833546462'/><link rel='self' type='application/atom+xml' href='http://www.blogger.com/feeds/5823906349768938190/posts/default/1468638523833546462'/><link rel='alternate' type='text/html' href='http://chandlertms.blogspot.com/2010/04/is-tms-needed.html' title='Is TMS needed ?????'/><author><name>Chandler TMS</name><uri>http://www.blogger.com/profile/17516475112889955131</uri><email>noreply@blogger.com</email><gd:image rel='http://schemas.google.com/g/2005#thumbnail' width='16' height='16' src='http://img2.blogblog.com/img/b16-rounded.gif'/></author><thr:total>0</thr:total></entry><entry><id>tag:blogger.com,1999:blog-5823906349768938190.post-1989633159484759407</id><published>2010-03-31T22:59:00.000-07:00</published><updated>2010-03-31T22:59:54.877-07:00</updated><title type='text'>New Treatment for Depression, NEUROSTAR TRANSCRANIAL MAGNETIC STIMULATION</title><content type='html'>&lt;span class="Apple-style-span" style="-webkit-border-horizontal-spacing: 2px; -webkit-border-vertical-spacing: 2px; border-collapse: collapse; font-family: arial, verdana, tahoma; font-size: 13px;"&gt;&lt;em&gt;&lt;span style="font-size: 10px;"&gt;&lt;div&gt;&lt;span class="Apple-style-span" style="-webkit-border-horizontal-spacing: 2px; -webkit-border-vertical-spacing: 2px; border-collapse: collapse; font-family: arial, verdana, tahoma;"&gt;&lt;span class="Apple-style-span" style="font-style: normal;"&gt;&lt;span class="Apple-style-span" style="font-size: x-large;"&gt;www.Chandlertms.com&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;/div&gt;&lt;div&gt;&lt;span class="Apple-style-span" style="-webkit-border-horizontal-spacing: 2px; -webkit-border-vertical-spacing: 2px; border-collapse: collapse; font-family: arial, verdana, tahoma;"&gt;&lt;span class="Apple-style-span" style="font-style: normal;"&gt;&lt;span class="Apple-style-span" style="font-size: x-large;"&gt;&lt;br /&gt;&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;/div&gt;&lt;span class="Apple-style-span" style="font-style: normal;"&gt;&lt;span class="Apple-style-span" style="font-size: x-large;"&gt;NeuroStar TMS Therapy® is indicated for the treatment of Major Depressive Disorder in adult patients who have failed to achieve satisfactory improvement from one prior antidepressant medication at or above the minimal effective dose and duration in the current episode&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;/em&gt;&lt;span class="Apple-style-span" style="font-size: x-large;"&gt;.&lt;/span&gt;&lt;/span&gt;&lt;span class="Apple-style-span" style="-webkit-border-horizontal-spacing: 2px; -webkit-border-vertical-spacing: 2px; border-collapse: collapse; font-family: arial, verdana, tahoma; font-size: 13px;"&gt;&lt;/span&gt;&lt;br /&gt;&lt;div style="color: black; font-family: arial, verdana, tahoma;"&gt;&lt;span class="Apple-style-span" style="font-size: x-large;"&gt;&lt;br /&gt;&lt;/span&gt;&lt;/div&gt;&lt;div style="color: black; font-family: arial, verdana, tahoma;"&gt;&lt;span class="Apple-style-span" style="font-size: x-large;"&gt;Transcranial Magnetic Stimulation (TMS)&amp;nbsp;Therapy uses short pulses of magnetic fields to stimulate nerve cells in the area of the brain thought to control mood.&amp;nbsp;&lt;/span&gt;&lt;/div&gt;&lt;div style="color: black; font-family: arial, verdana, tahoma;"&gt;&lt;span class="Apple-style-span" style="font-size: x-large;"&gt;TMS Therapy is performed in a psychiatrist’s office under their supervision while you remain awake and alert.&amp;nbsp;&lt;/span&gt;&lt;span class="Apple-style-span" style="font-size: x-large;"&gt;&lt;span class="Apple-style-span" style="color: black;"&gt;Neurostar TMS Therapy&amp;nbsp;&lt;/span&gt;&lt;/span&gt;&lt;span class="Apple-style-span" style="font-size: x-large;"&gt;is an outpatient procedure. The typical treatment course consists of 5 treatments per week over a 4-6 week period for 20-30 treatments. Each treatment session lasts approximately 37 minutes.&lt;/span&gt;&lt;/div&gt;&lt;div style="color: black; font-family: arial, verdana, tahoma; font-size: 13px; font-style: normal; font-weight: normal; text-decoration: none;"&gt;&lt;br /&gt;&lt;span class="Apple-style-span" style="font-size: x-small;"&gt;&lt;span class="Apple-style-span" style="font-size: 10px;"&gt;&lt;i&gt;&lt;br /&gt;&lt;/i&gt;&lt;/span&gt;&lt;/span&gt;&lt;/div&gt;&lt;div class="blogger-post-footer"&gt;&lt;img width='1' height='1' src='https://blogger.googleusercontent.com/tracker/5823906349768938190-1989633159484759407?l=chandlertms.blogspot.com' alt='' /&gt;&lt;/div&gt;</content><link rel='replies' type='application/atom+xml' href='http://chandlertms.blogspot.com/feeds/1989633159484759407/comments/default' title='Post Comments'/><link rel='replies' type='text/html' href='http://chandlertms.blogspot.com/2010/03/new-treatment-for-depression-neurostar.html#comment-form' title='0 Comments'/><link rel='edit' type='application/atom+xml' href='http://www.blogger.com/feeds/5823906349768938190/posts/default/1989633159484759407'/><link rel='self' type='application/atom+xml' href='http://www.blogger.com/feeds/5823906349768938190/posts/default/1989633159484759407'/><link rel='alternate' type='text/html' href='http://chandlertms.blogspot.com/2010/03/new-treatment-for-depression-neurostar.html' title='New Treatment for Depression, NEUROSTAR TRANSCRANIAL MAGNETIC STIMULATION'/><author><name>Chandler TMS</name><uri>http://www.blogger.com/profile/17516475112889955131</uri><email>noreply@blogger.com</email><gd:image rel='http://schemas.google.com/g/2005#thumbnail' width='16' height='16' src='http://img2.blogblog.com/img/b16-rounded.gif'/></author><thr:total>0</thr:total></entry></feed>
